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The Weekly Notable Startup Funding Report: 12/22/25 – AlleyWatch

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The Weekly Notable Startup Funding Report: 12/22/25 – AlleyWatch
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The Weekly Notable Startup Funding Report takes us on a trip across various ecosystems in the US, highlighting some of the notable funding activity in the various markets that we track. The notable startup funding rounds for the week ending 12/20/25 featuring funding details for Looma, Tebra, Orreco, and twenty-four other deals representing $6.4B in new funding that you need to know about.

Adaptive Security – $81.0M

New York-based Adaptive Security provides training and phishing simulations to help organizations strengthen human defenses against evolving cyber threats. Founded by Andrew Jones and Brian Long in 2023, Adaptive Security has now raised a total of $136.0M in total equity funding and is backed by Abstract, Andreessen Horowitz, Bain Capital Ventures, Capital One Ventures, Citi Ventures, NVentures, and OpenAI Startup Fund.

Aeovian Pharmaceuticals – $55.0M

San Francisco-based Aeovian Pharmaceuticals aims to discover, develop, and commercialize therapeutics for the treatment of rare and age-related diseases. Founded by James Peyer and Stelios Tzannis in 2012, Aeovian Pharmaceuticals has now raised a total of $142.0M in total equity funding and is backed by Apollo Health Ventures, CTI Life Sciences Fund, Foresite Capital, Hevolution, Luma Group, Sofinnova Investments, SymBiosis, The TSC Alliance Endowment Fund, venBio Partners, and Wilson Sonsini Goodrich & Rosati.

Chai Discovery – $130.0M

San Francisco-based Chai Discovery develops artificial intelligence models that predict and reprogram biochemical molecule interactions. Founded by Jack Dent, Jacques Boitreaud, Joshua Meier, and Matthew McPartlon in 2024, Chai Discovery has now raised a total of $230.0M in total equity funding and is backed by Dimension Capital, Emerson Collective, General Catalyst, Glade Brook Capital Partners, Lachy Groom, Menlo Ventures, Neo, Oak HC/FT, OpenAI, SV Angel, Thrive Capital, and Yosemite.

Clarity Pediatrics – $14.5M

San Francisco-based Clarity Pediatrics offers virtual pediatric healthcare focused on diagnosing and managing ADHD and anxiety in children and teens. Founded by Alesandro Larrazabal MD, FAAP, and Christina LaMontagne in 2021, Clarity Pediatrics has now raised a total of $24.5M in total equity funding and is backed by City Light Capital, GingerBread Capital, Homebrew, Jackson Square Ventures, MassMutual Catalyst Fund, Maverick Ventures, Operator Collective, Rethink Impact, and Scrub Capital.

Databricks – $4.0B

San Francisco-based Databricks is a data and AI platform that unifies data engineering, analytics, and machine learning on a lakehouse architecture. Founded by Ali Ghodsi, Andy Konwinski, Arsalan Tavakoli-Shiraji, Ion Stoica, Matei Zaharia, Patrick Wendell, and Reynold Xin in 2013, Databricks has now raised a total of $20.6B in total equity funding and is backed by Andreessen Horowitz, BlackRock, Blackstone Group, Coatue, Fidelity, GIC, Insight Partners, J.P. Morgan Asset Management, MGX, New Enterprise Associates, Ontario Teachers’ Pension Plan, Robinhood Ventures, T. Rowe Price, Temasek Holdings, Thrive Capital, and Winslow Capital.

DataLane – $22.5M

New York-based DataLane utilizes AI to transform unstructured local business data into organized contact information and market insights. Founded by David Patterson-Cole and Ganesh Thirumurthi in 2023, DataLane has now raised a total of $22.5M in total equity funding and is backed by Amplify Partners, Basis Set Ventures, Harry Stebbings, and Mischief.

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Echo – $35.0M

New York-based Echo develops and provides container base images designed to eliminate known software vulnerabilities in cloud-native applications. Founded by Eilon Elhadad and Eylam Milner in 2025, Echo has now raised a total of $50.0M in total equity funding and is backed by Hyperwise Ventures, N47, Notable Capital, SentinelOne, and Silicon Valley CISO Investments.

FINNY – $17.0M

New York-based FINNY is an AI-powered prospecting and marketing platform that helps financial advisors identify and connect with potential clients. Founded by Eden Ovadia, Theodore Janson, and Victoria Toli in 2023, FINNY has now raised a total of $21.8M in total equity funding and is backed by Activant Capital, Crossbeam Venture Partners, Hanover Technology Investment Management, Jason Wenk, Liquid 2 Ventures, Maple VC, Restive, Venrock, William McNabb, and Y Combinator.

Fluency – $40.0M

Burlington-based Fluency provides a digital advertising operating system that allows users to manage digital advertising campaigns across platforms. Founded by Brian McVey, Eric Mayhew, Michael Lane, and Scott Gale in 2017, Fluency has now raised a total of $41.0M in total equity funding and is backed by Integrity Growth Partners.

HawkEye 360 – $150.0M

Herndon-based HawkEye 360 detects, geolocates, and characterizesvarious RF signals using its satellite constellation in low Earth orbit. Founded by Charles Clancy, Chris DeMay, John Serafini, and Robert McGwier in 2015, HawkEye 360 has now raised a total of $522.3M in total equity funding and is backed by Hercules Capital, Pinegrove Capital Partners, and Silicon Valley Bank.

HEN Technologies – $20.0M

Hayward-based HEN Technologies develops an AI- and IoT-enabled fire suppression ecosystem to improve firefighting efficiency and responder safety. Founded by Sunny Sethi in 2020, HEN Technologies has now raised a total of $28.0M in total equity funding and is backed by Narotam Sekhsaria Family Office, O’Neil Strategic Capital, Tanas Capital, and z21 Ventures.

Homebound – $300.0M

Santa Rosa-based Homebound is a custom homebuilder that makes building the perfect home simple, transparent and human. Founded by Jack Abraham, Michael Richards, Nikki Pechet, and Tom O’Brien in 2018, Homebound has now raised a total of $528.4M in total equity funding and is backed by Atomic, Fifth Wall, Forerunner, Goldman Sachs, GV, Khosla Ventures, Magnetar Capital, and Thrive Capital.

Imprint – $150.0M

New York-based Imprint is a co-brand financial platform that designs, configures, and operates financial products in partnership and loyalty experiences. Founded by Daragh Murphy, Gaurav Ahuja, and Michael Pechman in 2020, Imprint has now raised a total of $352.0M in total equity funding and is backed by Hedosophia, Khosla Ventures, Kleiner Perkins, Ribbit Capital, Spice Expeditions, Thrive Capital, and Timeless.

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Last Energy – $100.0M

Washington-based Last Energy is a nuclear technology company that provides nuclear energy through its modular micro nuclear power plants. Founded by Bret Kugelmass in 2020, Last Energy has now raised a total of $164.0M in total equity funding and is backed by AE Ventures, Astera Institute, Galaxy Interactive, Gigafund, JAM Fund, The Haskell Company, Ultranative, and Woori Technology.

Looma – $10.0M

Durham-based Looma is an in-store digital media platform that focuses on storytelling, education, and recommendations. Founded by Cole Johnson in 2015, Looma has now raised a total of $22.6M in total equity funding and is backed by Staley Capital.

Lovable – $330.0M

Dover-based Lovable provides an AI-driven platform enabling users to generate and deploy web applications and websites from natural language prompts. Founded by Anton Osika and Fabian Hedin in 2023, Lovable has now raised a total of $552.5M in total equity funding and is backed by Accel, Atlassian Ventures, CapitalG, Creandum, Databricks Ventures, DST Global, EQT Growth, Evantic Capital, HubSpot Ventures, Khosla Ventures, Kinship Ventures, Menlo Ventures, NVentures, Salesforce Ventures, and T.Capital.

Mythic – $125.0M

Austin-based Mythic develops analog matrix processors and key cards based on analog compute-in-memory. Founded by Dave Fick and Mike Henry in 2012, Mythic has now raised a total of $289.7M in total equity funding and is backed by Atreides Management, Catapult Ventures, DCVC, Future Ventures, Honda Motor, Linse Capital, Lockheed Martin Ventures, New Enterprise Associates, One Madison Group, S3 Ventures, SBVA, and UDC Ventures.

Nirvana Insurance – $100.0M

San Francisco-based Nirvana Insurance offers A-rated commercial trucking insurance using telematics to enhance safety and reduce costs. Founded by Abhay Mitra, Alex Carges, and Rushil Goel in 2021, Nirvana Insurance has now raised a total of $262.2M in total equity funding and is backed by General Catalyst, Lightspeed Venture Partners, and Valor Equity Partners.

Octane – $50.0M

New York-based Octane is a fintech firm offering financing solutions for powersports, outdoor equipment, and recreational purchases. Founded by Andre Gregori, Daniel Petkevich, Mark Davidson, Mark Garro, and Michael Fanfant in 2014, Octane has now raised a total of $352.9M in total equity funding and is backed by Camping World, Good Sam, Holler-Classic Family of Dealerships, Huntington National Bank, Upper90, and Valar Ventures.

AlleyWatch’s exclusive coverage of this round – Octane Raises $100M to Scale Digital Financing Platform Across $150B Recreational Markets

Orreco – $4.0M

Cambridge-based Orreco provides biomarker analysis for athletes, federations, and professional franchises. Founded by Andrew Hodgson and Brian Moore in 2010, Orreco has now raised a total of $12.2M in total equity funding and is backed by Allain Roy, Enterprise Ireland, Graeme McDowell, Jason Calacanis, Mark Cuban, Padraig Harrington, The Twenty Minute VC, Todd Ramasar, and True Ventures.

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PolyAI – $86.0M

San Francisco-based PolyAI develops conversational artificial intelligence software that enables organizations to automate customer service interactions. Founded by Nikola Mrkšić, Pei-Hao Su, and Tsung-Hsien Wen in 2017, PolyAI has now raised a total of $202.0M in total equity funding and is backed by British Business Bank, Citi Ventures, Georgian, Hedosophia, Khosla Ventures, NVentures, Point72 Ventures, Sands Capital Ventures, Squarepoint Capital, and Zendesk Ventures.

Radiant – $300.0M

El Segundo-based Radiant develops portable nuclear microreactors designed to generate electricity and heat in a compact, factory-built form. Founded by Bob Urberger and Doug Bernauer in 2019, Radiant has now raised a total of $518.8M in total equity funding and is backed by Align Ventures, Andreessen Horowitz, ARK Venture Fund, Boost VC, Chevron Technology Ventures, DCVC, Draper Associates, Founders Fund, Friends & Family Capital, Giant Ventures, IQT, StepStone Group, Union Square Ventures, and Washington Harbour Partners.

Symbrosia – $5.8M

Kailua Kona-based Symbrosia is a cleantech startup reducing livestock methane with the mightiest seaweed. Founded by Alexia Akbay and Jonathan Simonds in 2018, Symbrosia has now raised a total of $14.2M in total equity funding and is backed by Idemitsu Kosan and One Small Planet.

Tebra – $250.0M

Corona Del Mar-based Tebra provide independent healthcare practices with digital tools and support to thrive in a new era of healthcare. Founded by Dan Rodrigues, Luke Kervin, and Travis Schneider in 2021, Tebra has now raised a total of $387.0M in total equity funding and is backed by Hildred Capital, HLM Venture Partners, Toba Capital, and Transformation Capital.

Vital Lyfe – $18.0M

Hawthorne-based Vital Lyfe is a Climatech product manufacturing firm that develops systems to produce safe drinking water from a range of natural sources. Founded by Andrew Harner and Jonathan Criss in 2024, Vital Lyfe has now raised a total of $36.1M in total equity funding and is backed by Also Capital, Cantos, General Catalyst, Generational Partners, Interlagos Capital, and Space.VC.

WearLinq – $14.0M

San Francisco-based WearLinq is a provider of wearable health monitoring and diagnosis solutions. Founded by Konrad Morzkowski in 2020, WearLinq has now raised a total of $26.3M in total equity funding and is backed by AIX Ventures, Alumni Ventures, Amino Capital, Angel School, Berkeley Catalyst Fund (BCF), Celtic House Asia Partners, Device of Tomorrow Capital, LDV Partners, Lightscape Partners, Maliam, NYX Ventures, Smartlink Partners, Solasta, SpringTide Ventures, and XB Ventures.

YSE Beauty – $15.0M

Los Angeles-based YSE Beauty develops and sells skincare products focused on addressing visible skin changes associated with hormonal shifts and aging. Founded by Molly Sims in 2023, YSE Beauty has now raised a total of $15.0M in total equity funding and is backed by Halogen Ventures, L Catterton, Silas Capital, and Willow Growth Partners.

The Weekly Notable Startup Funding Report: 12/22/25 – AlleyWatch

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